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Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli.

The stability of CTG triplet repeats was analyzed in Escherichia coli to identify processes responsible for their genetic instability. Using a biochemical assay for stability, we show that the absence of single-stranded-DNA-binding protein leads to an increase in the frequency of large deletions wit...

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Bibliografische Detailangaben
Veröffentlicht in:J Bacteriol
Hauptverfasser: Rosche, W A, Jaworski, A, Kang, S, Kramer, S F, Larson, J E, Geidroc, D P, Wells, R D, Sinden, R R
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178294/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8759875/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.16.5042-5044.1996
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