Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli.

The stability of CTG triplet repeats was analyzed in Escherichia coli to identify processes responsible for their genetic instability. Using a biochemical assay for stability, we show that the absence of single-stranded-DNA-binding protein leads to an increase in the frequency of large deletions wit...

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Main Authors: Rosche, W A, Jaworski, A, Kang, S, Kramer, S F, Larson, J E, Geidroc, D P, Wells, R D, Sinden, R R
Formato: Artigo
Idioma:Inglês
Publicado: 1996
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC178294/
https://ncbi.nlm.nih.gov/pubmed/8759875
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