Single-stranded DNA-binding protein enhances the stability of CTG triplet repeats in Escherichia coli.

The stability of CTG triplet repeats was analyzed in Escherichia coli to identify processes responsible for their genetic instability. Using a biochemical assay for stability, we show that the absence of single-stranded-DNA-binding protein leads to an increase in the frequency of large deletions wit...

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Bibliographic Details
Main Authors: Rosche, W A, Jaworski, A, Kang, S, Kramer, S F, Larson, J E, Geidroc, D P, Wells, R D, Sinden, R R
Format: Artigo
Language:Inglês
Published: 1996
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC178294/
https://ncbi.nlm.nih.gov/pubmed/8759875
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