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CD20-mediated apoptosis: signalling through lipid rafts
CD20 is an effective target for therapeutic B-cell depletion with monoclonal antibodies. One proposed mechanism of action is direct cytotoxicity mediated via tyrosine kinase-dependent signalling pathways activated upon CD20 cross-linking. The association of CD20 with membrane microdomains known as l...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Science Inc
2002
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782791/ https://ncbi.nlm.nih.gov/pubmed/12383196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01495.x |
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