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CD20-mediated apoptosis: signalling through lipid rafts

CD20 is an effective target for therapeutic B-cell depletion with monoclonal antibodies. One proposed mechanism of action is direct cytotoxicity mediated via tyrosine kinase-dependent signalling pathways activated upon CD20 cross-linking. The association of CD20 with membrane microdomains known as l...

詳細記述

保存先:
書誌詳細
主要な著者: Deans, Julie P, Li, Haidong, Polyak, Maria J
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Science Inc 2002
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782791/
https://ncbi.nlm.nih.gov/pubmed/12383196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01495.x
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