Endotoxin, but not platelet-activating factor, activates nuclear factor-κB and increases IκBα and IκBβ turnover in enterocytes

Bacterial endotoxin (lipopolysaccharide; LPS) and platelet-activating factor (PAF) are important triggers of bowel inflammation and injury. We have previously shown that LPS activates the transcription factor nuclear factor (NF)-κB in the intestine, which up-regulates many pro-inflammatory genes. Th...

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Autori principali: de Plaen, Isabelle G, Qu, Xiao-Wu, Wang, Hao, Tan, Xiao-Di, Wang, Liya, Han, Xin-Bing, Rozenfeld, Ranna A, Hsueh, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782741/
https://ncbi.nlm.nih.gov/pubmed/12153521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01453.x
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