Tetrahydrobiopterin prevents platelet-activating factor–induced intestinal hypoperfusion and necrosis: Role of neuronal nitric oxide synthase

OBJECTIVE: We reported previously that neuronal nitric oxide synthase (nNOS) is the predominant NOS in rat small intestine and is down-regulated by platelet-activating factor (PAF). The severity of the bowel injury induced by PAF is inversely related to its suppressing effect on nNOS. Here, we inves...

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Autori principali: Qu, Xiao-Wu, Thaete, Larry G., Rozenfeld, Ranna A., Zhu, Yaqin, De Plaen, Isabelle G., Caplan, Michael S., Hsueh, Wei
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2005
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1568387/
https://ncbi.nlm.nih.gov/pubmed/15891335
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