Accumulation of a potent γδ T-cell stimulator after deletion of the lytB gene in Escherichia coli

Activation of human Vγ9/Vδ2 T cells by many pathogens depends on the presence of small phosphorylated non-peptide compounds derived from the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway of isoprenoid biosynthesis. We here demonstrate that in Escherichia coli mutants deficient in lytB, an essent...

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Autors principals: Eberl, Matthias, Altincicek, Boran, Kollas, Ann-Kristin, Sanderbrand, Silke, Bahr, Ute, Reichenberg, Armin, Beck, Ewald, Foster, Donald, Wiesner, Jochen, Hintz, Martin, Jomaa, Hassan
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782719/
https://ncbi.nlm.nih.gov/pubmed/12047749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01414.x
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