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T-cell dynamics after high-dose chemotherapy in adults: elucidation of the elusive CD8(+) subset reveals multiple homeostatic T-cell compartments with distinct implications for immune competence

Recovery of total T cell numbers after in vivo T-cell depletion in humans is accompanied by complex perturbation within the CD8(+) subset. We aimed to elucidate the reconstitution of CD8(+) T cells by separate analysis of putative naïve CD95(−) CD28(+), memory CD95(+) CD28(+) and CD28(−) T cell comp...

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Autors principals: Fagnoni, Francesco F, Lozza, Laura, Zibera, Carlo, Zambelli, Alberto, Ponchio, Luisa, Gibelli, Nadia, Oliviero, Barbara, Pavesi, Lorenzo, Gennari, Roberto, Vescovini, Rosanna, Sansoni, Paolo, Da Prada, Gianantonio, Cuna, Gioacchino Robustelli Della
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782702/
https://ncbi.nlm.nih.gov/pubmed/11972629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01400.x
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