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Using Single Cell Transcriptomics to Elucidate the Myeloid Compartment in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is a dismal disease with a 5-year survival rate of 10%. A hallmark feature of this disease is its abundant microenvironment which creates a highly immunosuppressive milieu. This is, in large part, mediated by an abundant infiltration of myeloid cells in the PD...

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Detalhes bibliográficos
Main Authors: Padma Kadiyala, Ahmed M. Elhossiny, Eileen S. Carpenter
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-05-01
Colecção:Frontiers in Oncology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fonc.2022.881871/full
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