The regulation of DNAse activities in subcellular compartments of activated thymocytes

Thymocytes expressing self-reactive T-cell receptors (TCR) are eliminated in the thymus through a TCR-mediated signal. This cell death signal (negative selection) generates nuclear morphological change and DNA fragmentation in thymocytes. However, the pathway leading to DNA fragmentation of thymocyt...

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Autors principals: Nagata, Takuya, Kishi, Hiroyuki, Liu, Qin Li, Matsuda, Tadashi, Imanaka, Tsuneo, Tsukada, Kazuhiro, Kang, Dongchon, Muraguchi, Atsushi
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782686/
https://ncbi.nlm.nih.gov/pubmed/11985660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2002.01347.x
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