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Murine graft-versus-host disease induced using interferon-γ-deficient grafts features antibodies to double-stranded DNA, T helper 2-type cytokines and hypereosinophilia
Acute, lethal graft-versus-host disease (GvHD) develops in B6D2F(1) hybrid recipients of wild-type, C57BL/6, parental strain grafts; however, when interferon-γ (IFN-γ) gene knockout (gko) donors are used, the disease is prolonged and associated with a higher level of engraftment, particularly of T c...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782642/ https://ncbi.nlm.nih.gov/pubmed/11849316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0019-2805.2001.01353.x |
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