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Murine graft-versus-host disease induced using interferon-γ-deficient grafts features antibodies to double-stranded DNA, T helper 2-type cytokines and hypereosinophilia

Acute, lethal graft-versus-host disease (GvHD) develops in B6D2F(1) hybrid recipients of wild-type, C57BL/6, parental strain grafts; however, when interferon-γ (IFN-γ) gene knockout (gko) donors are used, the disease is prolonged and associated with a higher level of engraftment, particularly of T c...

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Bibliografiske detaljer
Main Authors: Ellison, Cynthia A, Bradley, David S, Fischer, Jacqie M M, Hayglass, Kent T, Gartner, John G
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782642/
https://ncbi.nlm.nih.gov/pubmed/11849316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0019-2805.2001.01353.x
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