Airway hyper-reactivity mediated by B-1 cell immunoglobulin M antibody generating complement C5a at 1 day post-immunization in a murine hapten model of non-atopic asthma

Contact skin immunization of mice with reactive hapten antigen and subsequent airway challenge with the same hapten induces immediate airflow obstruction and subsequent airway hyper-reactivity (AHR) to methacholine challenge, which is dependent on B cells but not on T cells. This responsiveness to a...

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Detalhes bibliográficos
Main Authors: Kawikova, Ivana, Paliwal, Vipin, Szczepanik, Marian, Itakura, Atsuko, Fukui, Mieko, Campos, Regis A, Geba, Gregory P, Homer, Robert J, Iliopoulou, Bettina P, Pober, Jordan S, Tsuji, Ryohei F, Askenase, Philip W
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782564/
https://ncbi.nlm.nih.gov/pubmed/15379984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01936.x
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