TLR9(−/−) and TLR9(+/+) mice display similar immune responses to a DNA vaccine

Plasmid DNA continues to attract interest as a potential vaccine-delivery vehicle. However, the mechanisms whereby immune responses are elicited by plasmids are not fully understood. Although there have been suggestions regarding the importance of CpG motifs in plasmid immunogenicity, the molecular...

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Detalhes bibliográficos
Main Authors: Babiuk, Shawn, Mookherjee, Neeloffer, Pontarollo, Reno, Griebel, Phillip, Van Drunen Littel-Van Den Hurk, Sylvia, Hecker, Rolf, Babiuk, Lorne
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782555/
https://ncbi.nlm.nih.gov/pubmed/15312142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01938.x
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