Modulation of immune responses to bovine herpesvirus-1 in cattle by immunization with a DNA vaccine encoding glycoprotein D as a fusion protein with bovine CD154

The objective of this study was to determine whether a DNA vaccine encoding bovine CD154 linked to a truncated version of bovine herpesvirus-1 (BHV-1) glycoprotein D (tgD-CD154) induces enhanced tgD-specific immune responses in cattle. In vitro characterization demonstrated that tgD and tgD-CD154 bo...

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Autors principals: Manoj, Sharmila, Griebel, Philip J, Babiuk, Lorne A, Van Drunen Littel-Van Den Hurk, Sylvia
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2004
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782479/
https://ncbi.nlm.nih.gov/pubmed/15147576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01877.x
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