Deficiency of BLNK hampers PLC-γ2 phosphorylation and Ca(2+) influx induced by the pre-B-cell receptor in human pre-B cells

B-cell linker protein (BLNK) is a component of the B-cell receptor (BCR) as well as of the pre-BCR signalling pathway, and BLNK(–/–) mice have a block in B lymphopoiesis at the pro-B/pre-B cell stage. A recent report described the complete loss or drastic reduction of BLNK expression in approximatel...

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Hlavní autoři: Taguchi, Tomoko, Kiyokawa, Nobutaka, Takenouch, Hisami, Matsui, Jun, Tang, Wei-Ran, Nakajima, Hideki, Suzuki, Kyoko, Shiozawa, Yusuke, Saito, Masahiro, Katagiri, Yohko U, Takahashi, Takao, Karasuyama, Hajime, Matsuo, Yoshinobu, Okita, Hajime, Fujimoto, Junichiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782531/
https://ncbi.nlm.nih.gov/pubmed/15270728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01918.x
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