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Deficiency of BLNK hampers PLC-γ2 phosphorylation and Ca(2+) influx induced by the pre-B-cell receptor in human pre-B cells
B-cell linker protein (BLNK) is a component of the B-cell receptor (BCR) as well as of the pre-BCR signalling pathway, and BLNK(–/–) mice have a block in B lymphopoiesis at the pro-B/pre-B cell stage. A recent report described the complete loss or drastic reduction of BLNK expression in approximatel...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Blackwell Science Inc
2004
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782531/ https://ncbi.nlm.nih.gov/pubmed/15270728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01918.x |
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