Increased expression of the natural killer cell inhibitory receptor CD85j/ILT2 on antigen-specific effector CD8 T cells and its impact on CD8 T-cell function

We investigated whether inhibitory natural killer cell receptor (iNKR) expression contributes to impaired antigen-specific cytotoxicity and interferon-γ (IFN-γ) production by CD8 T cells during chronic infection. iNKR immunoglobulin-like transcript-2 (ILT2/CD85j) is expressed on 40–55% of cytomegalo...

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Detalhes bibliográficos
Main Authors: Ince, M Nedim, Harnisch, Brooke, Xu, Zhan, Lee, Sang-Kyung, Lange, Christoph, Moretta, Lorenzo, Lederman, Michael, Lieberman, Judy
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782522/
https://ncbi.nlm.nih.gov/pubmed/15270723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2004.01907.x
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