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Distinct and Overlapping Effector Functions of Expanded Human CD4(+), CD8α(+) and CD4(-)CD8α(-) Invariant Natural Killer T Cells

CD1d-restricted invariant natural killer T (iNKT) cells have diverse immune stimulatory/regulatory activities through their ability to release cytokines and to kill or transactivate other cells. Activation of iNKT cells can protect against multiple diseases in mice but clinical trials in humans have...

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Autors principals: O'Reilly, Vincent, Zeng, Shijuan G., Bricard, Gabriel, Atzberger, Ann, Hogan, Andrew E., Jackson, John, Feighery, Conleth, Porcelli, Steven A., Doherty, Derek G.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3236218/
https://ncbi.nlm.nih.gov/pubmed/22174854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0028648
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