Insights into the regulation of immunoglobulin light chain gene rearrangements via analysis of the κ light chain locus in λ myeloma

Accumulating evidence indicates that B cells may undergo sequential rearrangements at the light chain loci, despite already expressing light chain receptors. This phenomenon may occur in the bone marrow and, perhaps, in germinal centers. As immunoglobulin (Ig)κ light chains usually rearrange before...

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Hlavní autoři: Perfetti, Vittorio, Vignarelli, Maurizio C, Palladini, Giovanni, Navazza, Valentina, Giachino, Claudia, Merlini, Giampaolo
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2004
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782513/
https://ncbi.nlm.nih.gov/pubmed/15196210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.2004.01902.x
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