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Factors affecting the susceptibility of the mouse pituitary gland to CD8 T-cell-mediated autoimmunity

We have previously shown, in a transgenic mouse model, that the pituitary gland is susceptible to CD8 T-cell-mediated autoimmunity, triggered by a cell-specific model autoantigen, resulting in pan-anterior pituitary hypophysitis and dwarfism. In the present study, we now demonstrate that antigen dos...

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Detalhes bibliográficos
Main Authors: De Jersey, James, Carmignac, Danielle, Le Tissier, Paul, Barthlott, Thomas, Robinson, Iain, Stockinger, Brigitta
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782418/
https://ncbi.nlm.nih.gov/pubmed/15009425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.01821.x
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