Cytoplasmic destruction of p53 by the endoplasmic reticulum-resident ubiquitin ligase ‘Synoviolin'

Synoviolin, also called HRD1, is an E3 ubiquitin ligase and is implicated in endoplasmic reticulum -associated degradation. In mammals, Synoviolin plays crucial roles in various physiological and pathological processes, including embryogenesis and the pathogenesis of arthropathy. However, little is...

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Main Authors: Yamasaki, Satoshi, Yagishita, Naoko, Sasaki, Takeshi, Nakazawa, Minako, Kato, Yukihiro, Yamadera, Tadayuki, Bae, Eunkyung, Toriyama, Sayumi, Ikeda, Rie, Zhang, Lei, Fujitani, Kazuko, Yoo, Eunkyung, Tsuchimochi, Kaneyuki, Ohta, Tomohiko, Araya, Natsumi, Fujita, Hidetoshi, Aratani, Satoko, Eguchi, Katsumi, Komiya, Setsuro, Maruyama, Ikuro, Higashi, Nobuyo, Sato, Mitsuru, Senoo, Haruki, Ochi, Takahiro, Yokoyama, Shigeyuki, Amano, Tetsuya, Kim, Jaeseob, Gay, Steffen, Fukamizu, Akiyoshi, Nishioka, Kusuki, Tanaka, Keiji, Nakajima, Toshihiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782373/
https://ncbi.nlm.nih.gov/pubmed/17170702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601490
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