Enhancement of DNA vaccine potency through linkage of antigen to filamentous bacteriophage coat protein III domain I

Although DNA-based cancer vaccines have been successfully tested in mouse models, a major drawback of cancer vaccination still remains, namely that tumour antigens are weak and fail to generate a vigorous immune response in tumour-bearing patients. Genetic technology offers strategies for promoting...

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Detalhes bibliográficos
Main Authors: Cuesta, Ángel M, Suárez, Eduardo, Larsen, Martin, Jensen, Kim Bak, Sanz, Laura, Compte, Marta, Kristensen, Peter, Álvarez-Vallina, Luis
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782252/
https://ncbi.nlm.nih.gov/pubmed/16556264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2006.02325.x
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