Tumor Immunotherapy Using Gene-Modified Human Mesenchymal Stem Cells Loaded into Synthetic Extracellular Matrix Scaffolds

Mesenchymal stem cells (MSCs) are appealing as gene therapy cell vehicles given their ease of expansion and transduction. However, MSCs exhibit immunomodulatory and proangiogenic properties that may pose a risk in their use in anticancer therapy. For this reason, we looked for a strategy to confine...

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Detalhes bibliográficos
Main Authors: Compte, Marta, Cuesta, Ángel M, Sánchez-Martín, David, Alonso-Camino, Vanesa, Vicario, José Luís, Sanz, Laura, Álvarez-Vallina, Luís
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Translational and Clinical Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729675/
https://ncbi.nlm.nih.gov/pubmed/19096041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0831
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