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Luminal bacterial antigen-specific CD4(+) T-cell responses in HLA-B27 transgenic rats with chronic colitis are mediated by both major histocompatibility class II and HLA-B27 molecules

Rats transgenic (TG) for the human major histocompatibility complex (MHC) class I HLA-B27 and β(2)-microglobulin genes develop chronic colitis under specific pathogen-free (SPF) but not sterile (germ-free, GF) conditions. We investigated the role of antigen-presenting molecules involved in generatin...

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Autors principals: Qian, Bi-Feng, Tonkonogy, Susan L, Sartor, R Balfour
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782237/
https://ncbi.nlm.nih.gov/pubmed/16476051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2005.02303.x
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