LIGHT is involved in the pathogenesis of rheumatoid arthritis by inducing the expression of pro-inflammatory cytokines and MMP-9 in macrophages

Macrophages play a crucial role in the perpetuation of inflammation and irreversible cartilage damage during the development of rheumatoid arthritis (RA). LIGHT (TNFSF14) and its receptor TR2 (TNFRSF14) are known to have pro-inflammatory activities in foam cells of atherosclerotic plaques. We tested...

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Bibliografske podrobnosti
Main Authors: Kim, Won-Jung, Kang, Yoon-Joong, Koh, Eun-Mi, Ahn, Kwang-Sung, Cha, Hoon-Suk, Lee, Won-Ha
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2005
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1782076/
https://ncbi.nlm.nih.gov/pubmed/15667572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2004.02004.x
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