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The genetic requirements for UmuDC-mediated cold sensitivity are distinct from those for SOS mutagenesis.

The umuDC operon of Escherichia coli, a member of the SOS regulon, is required for SOS mutagenesis. Following the posttranslational processing of UmuD to UmuD' by RecA-mediated cleavage, UmuD' acts in concert with UmuC, RecA, and DNA polymerase III to facilitate the process of translesion synthesis,...

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Bibliografische gegevens
Gepubliceerd in:J Bacteriol
Hoofdauteurs: Opperman, T, Murli, S, Walker, G C
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178205/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.15.4400-4411.1996
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