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A model for a umuDC-dependent prokaryotic DNA damage checkpoint

The products of the Escherichia coli umuDC operon are required for translesion synthesis, the mechanistic basis of most mutagenesis caused by UV radiation and many chemicals. The UmuD protein shares homology with LexA, the repressor of SOS-regulated loci, and similarly undergoes a facilitated autodi...

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Bibliografski detalji
Glavni autori: Opperman, Timothy, Murli, Sumati, Smith, Bradley T., Walker, Graham C.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC17760/
https://ncbi.nlm.nih.gov/pubmed/10430923
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