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Cyclooxygenase-2 inhibitors: promise or peril?

The discovery of two isoforms of the cyclooxygenase enzyme, COX-1 and COX-2, and the development of COX-2-specific inhibitors as anti-inflammatories and analgesics have offered great promise that the therapeutic benefits of NSAIDs could be optimized through inhibition of COX-2, while minimizing thei...

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Bibliografiske detaljer
Main Authors: Mengle-Gaw, Laurel J, Schwartz, Benjamin D
Format: Artigo
Sprog:Inglês
Udgivet: 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781678/
https://ncbi.nlm.nih.gov/pubmed/12467519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/09629350290000041
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