The role of X-chromosome inactivation in female predisposition to autoimmunity

INTRODUCTION: A reduction in the sex ratio (male : female) is characteristic of most autoimmune disorders. The increased prevalence in females ranges from a modest 2:1 for multiple sclerosis [1], to approximately 10:1 for systemic lupus erythematosus [2]. This tendency toward autoimmunity in females...

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Bibliografiske detaljer

Udgivet i:	Arthritis Res
Principais autores:	Chitnis, Smita, Monteiro, Joanita, Glass, David, Apatoff, Brian, Salmon, Jane, Concannon, Patrick, Gregersen, Peter K
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2000
Fag:	Primary Research
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17816/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11056674/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar118
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