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Suppression of matrix metalloproteinase-9 production from neutrophils by a macrolide antibiotic, roxithromycin, in vitro.

BACKGROUND: Macrolide antibiotics such as erythromycin and roxithromycin (RXM) have an anti-inflammatory effect that may account for their clinical benefit in the treatment of chronic airway inflammatory diseases. However, the precise mechanism of this anti-inflammatory effect is not well understood...

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Bibliographic Details
Main Authors: Kanai, Ken-Ichi, Asano, Kazuhito, Hisamitsu, Tadashi, Suzaki, Harumi
Format: Artigo
Language:Inglês
Published: 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781582/
https://ncbi.nlm.nih.gov/pubmed/15770046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/S0962935104000468
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