ERK1 and ERK2 mitogen-activated protein kinases affect Ras-dependent cell signaling differentially

BACKGROUND: The mitogen-activated protein (MAP) kinases p44(ERK1 )and p42(ERK2 )are crucial components of the regulatory machinery underlying normal and malignant cell proliferation. A currently accepted model maintains that ERK1 and ERK2 are regulated similarly and contribute to intracellular signa...

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Bibliographic Details
Main Authors: Vantaggiato, Chiara, Formentini, Ivan, Bondanza, Attilio, Bonini, Chiara, Naldini, Luigi, Brambilla, Riccardo
Format: Artigo
Language:Inglês
Published: BioMed Central 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781522/
https://ncbi.nlm.nih.gov/pubmed/16805921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/jbiol38
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