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High glucose upregulates connective tissue growth factor expression in human vascular smooth muscle cells
BACKGROUND: Connective tissue growth factor (CTGF) is a potent profibrotic factor, which is implicated in fibroblast proliferation, angiogenesis and extracellular matrix (ECM) synthesis. It is a downstream mediator of some of the effects of transforming growth factor β (TGFβ) and is potentially indu...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1781444/ https://ncbi.nlm.nih.gov/pubmed/17224075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-8-1 |
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