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Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis.

Mycobacterium tuberculosis is a natural mutant with inactivated oxidative stress regulatory gene oxyR. This characteristic has been linked to the exquisite sensitivity of M. tuberculosis to isonicotinic acid hydrazide (INH). In the majority of mycobacteria tested, including M. tuberculosis, oxyR is...

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Bibliografski detalji
Izdano u:J Bacteriol
Glavni autori: Dhandayuthapani, S, Zhang, Y, Mudd, M H, Deretic, V
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1996
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8655566/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.12.3641-3649.1996
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