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Oxidative stress response and its role in sensitivity to isoniazid in mycobacteria: characterization and inducibility of ahpC by peroxides in Mycobacterium smegmatis and lack of expression in M. aurum and M. tuberculosis.

Mycobacterium tuberculosis is a natural mutant with inactivated oxidative stress regulatory gene oxyR. This characteristic has been linked to the exquisite sensitivity of M. tuberculosis to isonicotinic acid hydrazide (INH). In the majority of mycobacteria tested, including M. tuberculosis, oxyR is...

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Podrobná bibliografie
Vydáno v:J Bacteriol
Hlavní autoři: Dhandayuthapani, S, Zhang, Y, Mudd, M H, Deretic, V
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1996
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC178138/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8655566/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.178.12.3641-3649.1996
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