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Structural plasticity and Mg(2+) binding properties of RNase P P4 from combined analysis of NMR residual dipolar couplings and motionally decoupled spin relaxation

The P4 helix is an essential element of ribonuclease P (RNase P) that is believed to bind catalytically important metals. Here, we applied a combination of NMR residual dipolar couplings (RDCs) and a recently introduced domain-elongation strategy for measuring “motionally decoupled” relaxation data...

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Detalhes bibliográficos
Main Authors: Getz, Melissa M., Andrews, Andy J., Fierke, Carol A., Al-Hashimi, Hashim M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1781369/
https://ncbi.nlm.nih.gov/pubmed/17194721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.264207
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