Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis

The present study was designed to analyze the level of B-cell clonal diversity in patients with rheumatoid arthritis by using HCDR3 (third complementarity determining region of the rearranged heavy chain variable region gene) length as a marker. A modified immunoglobulin V(H) gene fingerprinting met...

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Autors principals: Itoh, Kenji, Patki, Varsha, Furie, Richard A, Chartash, Elliot K, Jain, Rita I, Lane, Lewis, Asnis, Stanley E, Chiorazzi, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2000
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC17803/
https://ncbi.nlm.nih.gov/pubmed/11219389
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