Growth Regulation via Insulin-Like Growth Factor Binding Protein-4 and -2 in Association with Mutant K-ras in Lung Epithelia

Gain-of-function point mutations in K-ras affect early events in pulmonary bronchioloalveolar carcinoma. We investigated altered mRNA expression on K-Ras activation in human peripheral lung epithelial cells (HPL1A) using oligonucleotide microarrays. Mutated K-Ras stably expressed in HPL1A accelerate...

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Hlavní autoři: Sato, Hanako, Yazawa, Takuya, Suzuki, Takehisa, Shimoyamada, Hiroaki, Okudela, Koji, Ikeda, Masaichi, Hamada, Kenji, Yamada-Okabe, Hisafumi, Yao, Masayuki, Kubota, Yoshinobu, Takahashi, Takashi, Kamma, Hiroshi, Kitamura, Hitoshi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1780191/
https://ncbi.nlm.nih.gov/pubmed/17071580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051068
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