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A Rate Equation Approach to Elucidate the Kinetics and Robustness of the TGF-β Pathway

We present a rate equation model for the TGF-β pathway in endothelial cells together with novel measurements. This pathway plays a prominent role in inter- and intracellular communication and subversion can lead to cancer, fibrosis vascular disorders, and immune diseases. The model successfully desc...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Melke, Pontus, Jönsson, Henrik, Pardali, Evangelia, ten Dijke, Peter, Peterson, Carsten
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2006
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779910/
https://ncbi.nlm.nih.gov/pubmed/17012329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080408
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