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A Rate Equation Approach to Elucidate the Kinetics and Robustness of the TGF-β Pathway

We present a rate equation model for the TGF-β pathway in endothelial cells together with novel measurements. This pathway plays a prominent role in inter- and intracellular communication and subversion can lead to cancer, fibrosis vascular disorders, and immune diseases. The model successfully desc...

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Detalhes bibliográficos
Main Authors: Melke, Pontus, Jönsson, Henrik, Pardali, Evangelia, ten Dijke, Peter, Peterson, Carsten
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779910/
https://ncbi.nlm.nih.gov/pubmed/17012329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.080408
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