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Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice

Cholecystokinin (CCK)-induced pancreatic growth in mice involves parallel increases in DNA and protein. The mammalian target of rapamycin (mTOR) signalling pathway regulates mRNA translation and its activation is implicated in growth of various tissues. The aim of this study was to elucidate whether...

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Autors principals: Crozier, Stephen J, Sans, M Dolors, Guo, LiLi, D'Alecy, Louis G, Williams, John A
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779746/
https://ncbi.nlm.nih.gov/pubmed/16613881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.106914
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