Human TRPC6 expressed in HEK 293 cells forms non-selective cation channels with limited Ca(2+) permeability

TRPC6 is thought to be a Ca(2+)-permeable cation channel activated following stimulation of G-protein-coupled membrane receptors linked to phospholipase C (PLC). TRPC6 current is also activated by exogenous application of 1-oleoyl-acetyl-sn-glycerol (OAG) or by inhibiting 1,2-diacylglycerol (DAG) li...

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Autores principales: Estacion, Mark, Sinkins, William G, Jones, Stephen W, Applegate, Milana A B, Schilling, William P
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2006
Materias:
Cellular
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779672/
https://ncbi.nlm.nih.gov/pubmed/16439426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.103143
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