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Concanavalin-A reports agonist-induced conformational changes in the intact GluR6 kainate receptor

The agonist-binding domain of ionotropic glutamate receptors (iGluRs) has recently been crystallized as two polypeptide chains with a linker region. Although work on the structure of this isolated ligand-binding core has been invaluable, there is debate over how it relates to conformations adopted b...

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Main Authors: Fay, Anne-Marie L, Bowie, Derek
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779634/
https://ncbi.nlm.nih.gov/pubmed/16439423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2005.103580
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