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Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

We report the crystal structure of the glycosylated ligand-binding (S1S2) domain of the kainate receptor subunit GluR6, in complex with the agonist domoate. The structure shows the expected overall homology with AMPA and NMDA receptor subunit structures but reveals an unexpected binding mode for the...

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Detalhes bibliográficos
Main Authors: Nanao, Max H., Green, Tim, Stern-Bach, Yael, Heinemann, Stephen F., Choe, Senyon
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC547884/
https://ncbi.nlm.nih.gov/pubmed/15677325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409573102
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