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Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid
We report the crystal structure of the glycosylated ligand-binding (S1S2) domain of the kainate receptor subunit GluR6, in complex with the agonist domoate. The structure shows the expected overall homology with AMPA and NMDA receptor subunit structures but reveals an unexpected binding mode for the...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC547884/ https://ncbi.nlm.nih.gov/pubmed/15677325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409573102 |
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