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Structure of the kainate receptor subunit GluR6 agonist-binding domain complexed with domoic acid

We report the crystal structure of the glycosylated ligand-binding (S1S2) domain of the kainate receptor subunit GluR6, in complex with the agonist domoate. The structure shows the expected overall homology with AMPA and NMDA receptor subunit structures but reveals an unexpected binding mode for the...

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Bibliografske podrobnosti
Main Authors: Nanao, Max H., Green, Tim, Stern-Bach, Yael, Heinemann, Stephen F., Choe, Senyon
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC547884/
https://ncbi.nlm.nih.gov/pubmed/15677325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0409573102
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