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Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution

BACKGROUND: Systematic analyses of loss-of-function phenotypes have been carried out for most genes in Saccharomyces cerevisiae, Caenorhabditis elegans, and Drosophila melanogaster. Although such studies vastly expand our knowledge of single gene function, they do not address redundancy in genetic n...

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Detalhes bibliográficos
Main Authors: Tischler, Julia, Lehner, Ben, Chen, Nansheng, Fraser, Andrew G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779603/
https://ncbi.nlm.nih.gov/pubmed/16884526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2006-7-8-r69
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