SIV(SM)/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells

BACKGROUND: Vpx is a non-structural protein coded by members of the SIV(SM)/HIV-2 lineage that is believed to have originated by duplication of the common vpr gene present in primate lentiviruses. Vpx is incorporated into virion particles and is thus present during the early steps of viral infection...

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Main Authors: Goujon, Caroline, Rivière, Lise, Jarrosson-Wuilleme, Loraine, Bernaud, Jeanine, Rigal, Dominique, Darlix, Jean-Luc, Cimarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2007
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1779362/
https://ncbi.nlm.nih.gov/pubmed/17212817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-4-2
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