Heterologous Human Immunodeficiency Virus Type 1 Lentiviral Vectors Packaging a Simian Immunodeficiency Virus-Derived Genome Display a Specific Postentry Transduction Defect in Dendritic Cells

Heterologous lentiviral vectors (LVs) represent a way to address safety concerns in the field of gene therapy by decreasing the possibility of genetic recombination between vector and packaging constructs and the generation of replication-competent viruses. Using described LVs based on human immunod...

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Detalhes bibliográficos
Main Authors: Goujon, Caroline, Jarrosson-Wuilleme, Loraine, Bernaud, Jeanine, Rigal, Dominique, Darlix, Jean-Luc, Cimarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187397/
https://ncbi.nlm.nih.gov/pubmed/12915545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9295-9304.2003
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