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The pharmacokinetics of neostigmine and 3-hydroxyphenyltrimethyl-ammonium in the rat: Dose-dependent effects after portal vein administration

1 The elimination kinetics of [(14)C]-neostigmine iodide and [(14)C]-3-hydroxyphenyltrimethyl-ammonium iodide (3-OH PTMA) have been studied in the rat. 2 The presence of a renal secretory pathway for neostigmine and 3-OH PTMA has been confirmed. 3 For neostigmine and 3-OH PTMA, at a given dose level...

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Détails bibliographiques
Auteurs principaux: Barber, H.E., Bourne, G.R.
Format: Artigo
Langue:Inglês
Publié: 1974
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776893/
https://ncbi.nlm.nih.gov/pubmed/4455331
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