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The pharmacokinetics of pyridostigmine and 3-hydroxy-N-methylpyridinium in the rat: dose-dependent effects after portal vein administration.

1 The elimination kinectis of [14C]-pyridostigmine iodine and [14-C-methyl]-3-hydroxypyridinium bromide (3-OH NMP) have been studied in the rat. 2 For pyridostigmine, at a given dose level, the fraction of the dose eliminated unchanged was reduced and the metabolite fraction was increased after port...

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Bibliografiske detaljer
Main Authors: Barber, H E, Bourne, G R, Calvey, T N, Muir, K T
Format: Artigo
Sprog:Inglês
Udgivet: 1975
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1666696/
https://ncbi.nlm.nih.gov/pubmed/173444
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