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Further evidence for a central hypotensive action of α-methyldopa in both the rat and cat
1. α-Methyldopa (300 mg/kg i.p.) produced a fall in blood pressure in conscious genetic hypertensive rats. Pretreatment with intraventricular 6-hydroxydopamine prevented this hypotensive effect of α-methyldopa, whilst intravenous 6-hydroxydopamine reduced but did not prevent the hypotension. 2. The...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1973
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1776563/ https://ncbi.nlm.nih.gov/pubmed/4722038 |
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