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Further evidence for a central hypotensive action of α-methyldopa in both the rat and cat

1. α-Methyldopa (300 mg/kg i.p.) produced a fall in blood pressure in conscious genetic hypertensive rats. Pretreatment with intraventricular 6-hydroxydopamine prevented this hypotensive effect of α-methyldopa, whilst intravenous 6-hydroxydopamine reduced but did not prevent the hypotension. 2. The...

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Autors principals: Finch, L., Haeusler, G.
Format: Artigo
Idioma:Inglês
Publicat: 1973
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776563/
https://ncbi.nlm.nih.gov/pubmed/4722038
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