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Brain levels of Δ(1)-tetrahydro-cannabinol and its metabolites in mice tolerant to the hypothermic effect of Δ(1)-tetrahydrocannabinol

Repeated voluntary consumption of cannabis in milk (approximately 8 mg per day for 15 days) produced in mice tolerance to the hypothermic effect of tritiated Δ(1)-tetrahydrocannabinol ([(3)H]-Δ(1)-THC; 2 mg/kg i.v.) but not to the effect of [(3)H]-Δ(1)-THC on immobility index. The development of tol...

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Detalhes bibliográficos
Main Authors: Lawrence, D. K., Pertwee, R. G.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776396/
https://ncbi.nlm.nih.gov/pubmed/4793443
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