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Anaphylaxis in the guinea-pig isolated heart: Selective inhibition by burimamide of the positive inotropic and chronotropic effects of released histamine

1. Anaphylaxis was induced in the isolated heart of the guinea-pig in the presence of burimamide at concentrations of 4 × 10(-5)M and 2·7 × 10(-4)M. 2. Burimamide did not affect the immunological release of histamine; however, it selectively antagonized the positive inotropic and chronotropic effect...

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Detalhes bibliográficos
Main Authors: Capurro, Norine, Levi, R.
Formato: Artigo
Idioma:Inglês
Publicado em: 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1776149/
https://ncbi.nlm.nih.gov/pubmed/4132778
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